Nicotinamide N-methyltransferase (NNMT) is an enzyme involved in fat metabolism, and inhibiting it can help manage body composition. 5-amino 1MQ, an NNMT inhibitor, has shown promising results in reducing body weight and shrinking fat cells, making it a potential tool for addressing obesity and improving fat distribution.
Berberine, a plant-based compound, reduces fat production by inhibiting fat-forming genes, aiding in weight management and improving metabolic health. It also lowers insulin resistance, has a positive impact on cholesterol levels, and supports a diverse gut microbiome.